freqAnalysis A program for the statistical analysis of nucleotide motifs.
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freqAnalysis Description

freqAnalysis was designed to identify statistically aberrant k-length nucleotide motifs in coding DNA sequences, specifically to identify putative programmed translational frameshift sites. These are short sequences capable of inducing highly efficient ribosomal frameshifting by destabilizing normal ribosome-mRNA interaction. Because of the potentially catastrophic effect of frameshifting on normal protein production, we reasoned, such sites would be selected against by evolution and hence statistically underrepresented in protein-encoding sequences. Give freqAnalysis a try to see what it's really capable of!

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