TreeFit

Genetic data analysis made easy.
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TreeFit Ranking & Summary

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  • Rating:
  • License:
  • Freeware
  • Publisher Name:
  • Steven Kalinowski
  • Operating Systems:
  • Windows All
  • File Size:
  • 82 KB

TreeFit Tags


TreeFit Description

Evolutionary trees are frequently used to describe genetic relationships between populations. Hierarchical, bifurcating trees are a reasonable model for the evolution of DNA sequences and species, but may or may not be appropriate for describing population structrue in populations connected by gene flow. For example, if populations are arranged in a stepping stone pattern, the genetic relationships between populations will not follow a hierarchical pattern, and traditional neighbor-joining or UPGMA trees may not be appropriate tools for describing the structure of such populations. TreeFit is a simple application developed to help you analyze how well a tree fits the genetic data the tree was calculated from. TreeFit creates neighbor-joining and UPGMA trees from a genetic distance matrix, and then compares the observed genetic distance between populations with the genetic distance in the tree. The similarity between these distances is express as R-squared, the familiar statistic used to summarize the scatter of points around a least-squares regression line.


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