 | SNVerDetection of rare and common variants in next generation sequencing |
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SNVer Description
SNVer is a statistical instrument specially designed in order to call common and rare variants in the analysis of pool or individual next-generation sequencing data. The program reports one single overall p-value for evaluating the significance of a candidate locus being a variant, based on which multiplicity control can be obtained. Loci with any (low) coverage can be tested and depth of coverage will be quantitatively factored into final significance calculation. SNVer runs very fast, making it feasible for analysis of whole-exome sequencing data.
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