JVirGel A software for the simulation and analysis of proteomics data
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JVirGel Description

JVirGel is a powerful application designed to determine the theoretical isoelectric points (pI) and the calculated molecular weights (MW) of proteins. It also enables you to visualize these as a virtual two-dimensional (2D) protein map. The user is able to control the presentation of the calculated 2D gel interactively by selecting a pI/MW range and an electrophoretic timescale of interest. Main features: Import of amino acid sequences from FASTA-, EMBL-file or from PRODORIC database via XML Prediction and visualisation of secretomes Prediction and visualisation of membrane proteomes Translation of the Codon Adaptation Index (CAI) into protein spot size Exclusion of membrane proteins from the visualisation Accounting for signal peptides and in silico cleavage that results in a higher prediction accuracy of the pI and MW Export of virtual gels to png- or jpg-graphics Matching of an experimental gel with a virtual gel using different regression algorithms Zooms into an user selectable pH/MW range Proteins can be sorted into groups and all data can be exported in CSV-tables or MS-Excel spreadsheets Proteins can be colored according to their content of transmembrane-helices or their probability to be secreted

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