KINGROUP A program for pedigree relationship reconstruction and kin group assignments using genetic markers
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genetic reconstruct Marker pedigree relationship pedigree reconstruction genetic markers

KINGROUP Description

A program for pedigree relationship reconstruction and kin group assignments using genetic markers The estimation of population frequencies of codominant genetic markers from samples with unknown kin structures is of paramount importance to the population genetic studies, since they form the foundation for downstream genetic analyses.The frequencies can be used to estimate, for instance, the genetic distance between two populations, or the effective population size. Similarly, deviations from Hardy-Weinberg Equilibrium (HWE) of these alleles can be used to assess past effects on the genetic structure of the population due to, for instance, genetic drift, inbreeding and genetic bottlenecks. The population frequencies are normally estimated from a large sample of assumed to be unrelated individuals.In practice, it may be difficult to acquire genotypes from free-living individuals fulfilling this basic assumption of sampling population frequencies and often samples contain a mixture of related genotypes from multiple generations.Currently, it is unknown how the population allele frequencies can be reliably estimated when actual pedigrees within data sets are unknown and have to be assessed simultaneously. Although this may not matter for large sample sizes within a randomly interbreeding population, where all individuals contribute equally to the next generation, this certainly will matter for small samples from populations wherein some individuals are more productive than others.Considering this, the KINGROUP program aims to offer you a simple and handy tool for visually studying the way pedigree relationship reconstruction work. Requirements: · Java

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