Gain An easy-to-use Java tool that lets you play with different genetic associations
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simulate genetic association SNP interaction genetic association nucleotide polymorphism

Gain Description

An easy-to-use Java tool that lets you play with different genetic associations GAIN or in other words, the Genetic Association Interaction Network tool, is based on the interaction information between three attributes; in this case, between two single nucleotide polymorphismus (SNPs) and a class or phenotype attribute.Interaction information is the gain in phenotype information obtained by considering SNP A and SNP B jointly beyond the phenotype information that would be gained by considering SNPs A and B independently. Thus, each edge in a GAIN represents the increase in information about the phenotype achieved by considering the two SNPs jointly compared to the expected increase in information with the assumption of independence between the SNPs. The developer has emphasized that a connection between SNPs in a GAIN is specific to the given phenotype because it measures the correlation between two SNPs that influences association with the phenotype. The network can be exported to Cytoscape or visualized interactively within the GAIN tool. Requirements: · Java

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